产品信息
|
| 中文名 |
他克莫司 |
| 中文同义 |
大环哌喃;他克莫斯;泰克利马;他克莫司FK-506;(1R,9S,12S,13R,14S,17R,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-{1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo[22.3.1.0鈦?鈦筣octacos-18-ene-2,3,10,16-tetrone;(1R,9S,12S,13R,14S,17R,21S,23S,24R,25S,27R)-1,14-DIHYDROXY-12-{1-[(1R,3R,4R)-4-HYDROXY-3-METHOXYCYCLOHEXYL]PROP-1-EN-2-YL}-23,25-DIMETHOXY-13,19,21,27-TETRAMETHYL-17-(PROP-2-EN-1-YL)-11,28-DIOXA-4-AZATRICYCLO[22.3.1.0鈦鈦筣OCTACOS-18-ENE-2,3,10,16-TETRONE;他克莫司, ≥98%(HPLC);他克莫司标准品 |
| 英文名 |
Tacrolimus |
| 英文同义 |
(2-propenyl)-,(3s-(3r*(e(1s*,3s*,4s*)),4s*,5r*,8s*,9e,12r*,14r*,15s*,16r*,18s*;,19s*,26ar*))-;16-dimethoxy-4,10,12,18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;L 679934;Protopic;FK-506：FR-900506;Fujimycin Prozraf |
| CAS |
104987-11-3 |
| 分子式 |
C44 H69 N O12 |
| 分子量 |
804.02 |
| EINECS |
1308068-626-2 |
| 相关类别 |
医用原料;中间体;微生物代谢物;标准品;信号转导通路激酶抑制剂;中药对照品;分析标准品;植物提取物;Dermatosis皮肤美容类;原料药;大环内酰胺类抗生素;抗生素;药物;科研试剂;免疫抑制剂;药物标准品;中药标准品;医药中间体;小分子抑制剂;Inhibitors;小分子抑制剂，天然产物;医药原料药;化合物;医药原料;原料;分析试剂标准品;对照品-中药对照品;化工中间体;标准品 -中药标准品;科研原药系列;化工中间体工业原料;医药、农药及染料中间体;医药化工类;Active Pharmaceutical Ingredients;Immunosuppressant.;Intermediates & Fine Chemicals;Pharmaceuticals;API;Chiral Reagents;Fujimycin, Prograf;antibiotic;APIs |
| 结构式 |
 |
性质
|
| 熔点 |
113-115°C |
| 沸点 |
871.7±75.0 °C(Predicted) |
| 密度 |
1.19±0.1 g/cm3(Predicted) |
| 闪点 |
2℃ |
| 储存条件 |
−20°C
|
| 溶解度 |
DMSO: >3 mg/mL
|
| 酸度系数(pKa) |
9.97±0.70(Predicted) |
| 形态 |
solid
|
| 颜色 |
white
|
| 水溶解性 |
Freely soluble in DMSO or ethanol. Poorly soluble in water.Soluble in dimethyl sulfoxide, ethanol, water, acetone, chloroform, ethyl acetate, ether, methanol and dimethyl formamide. |
| InChIKey |
QJJXYPPXXYFBGM-LFZNUXCKSA-N |
